BILE EFFECTS ON THE PSEUDOMONAS AERUGINOSA PATHOGENESIS IN CYSTIC FIBROSIS PATIENTS WITH GASTROESOPHAGEAL REFLUX

Bile effects on the Pseudomonas aeruginosa pathogenesis in cystic fibrosis patients with gastroesophageal reflux

Gastroesophageal reflux (GER) occurs in most cystic fibrosis (CF) patients and is the primary source of bile aspiration in the airway tract of CF individuals.Aspirated bile is associated with the severity of lung diseases and chronic inflammation caused by Pseudomonas aeruginosa as the most common pathogen of CF respiratory tract infections.P.aerug

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Model FRBR in origin

Objective.This article aims at identifying the genesis of the studies the conceptual model Functional Requirements for Bibliographic Records (FRBR), published in 1998 by the International Federation of Library Associations and Institutions (IFLA) Steak Knives with the proposal to develop new approach to the bibliographic record.Method.For this appe

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